MDMA (Ecstasy, Molly) stays in the system for 3-5 days, but detection duration depends on the type of test used. It can be detected in blood and saliva for up to 1-2 days, in urine for 2-4 days (up to a week for heavy users), and in hair follicles for up to 90 days or longer. These detection windows can vary with usage patterns, individual metabolism, and test sensitivity, with urine tests being the most common for detecting recent use while hair tests reveal longer-term usage.
About 14% of adults reported using drugs in the past year. Among those, 24% indicated they had previously used MDMA, according to Wu, T., et al (2009) study titled, “The High Prevalence of Substance Use Disorders Among Recent MDMA Users Compared With Other Drug Users” published in the Journal of Addictive Behaviors.
Several factors influence how long MDMA remains detectable. These include the dose and frequency of use, the individual’s metabolic rate, body composition (body fat and muscle mass), hydration levels, age, health status, and the method of consumption (oral, snorted, etc.). For example, higher body fat can prolong the elimination process since metabolites accumulate in fatty tissue. Fast metabolizers clear the drug quickly, while chronic or heavy users may retain MDMA longer.
The common withdrawal symptoms of MDMA include fatigue, depression, loss of appetite, irritability, anxiety, agitation, increased appetite, and excessive sleepiness. Withdrawal symptoms generally start within 24 hours of last use and may last 3-5 days; withdrawal severity can be influenced by usage history and co-occurring mental health issues. To get MDMA out of the system, time is the only reliable factor; there is no proven way to speed up elimination.
Maintaining hydration and good health supports natural detoxification, but drinking excessive water or exercising immediately after use is not recommended and can be harmful. For those struggling with addiction, professional detox and treatment programs provide medically supervised support for withdrawal and recovery.
What Factors Impact How Long MDMA Stays in Your System?
The common factors that impact how long MDMA stays in your system include dosage, frequency of use, metabolism, age, and body composition.
The prevalence is estimated at 0.18% among children and adolescents (10-17 years) and about 0.13% among adults (18-75 years), according to a 2023 research titled “Survey On Addiction Of Drugs” published in the Azadi Ka Amrit Journal.
The common factors that impact how long MDMA stays in your system are listed below.
- Dosage: Higher doses of MDMA take longer to metabolize and eliminate from the body, which extends the detection time. Larger amounts need more processing time by the liver, leading to a prolonged presence in bodily fluids.
- Frequency of use: Regular or repeated use causes MDMA and its metabolites to accumulate in the body, lengthening the time it remains detectable. Especially with frequent use, elimination times can increase significantly compared to single or occasional use.
- Metabolism: Individual metabolic rates vary due to genetics, age, and overall health, influencing how quickly MDMA is processed. People with faster metabolisms break down and clear the drug more rapidly than those with slower metabolism.
- Age: Younger individuals metabolize and excrete drugs faster than older adults, who tend to have slower drug clearance due to decreased metabolic and organ function. Therefore, age impacts the drug’s elimination timeline.
- Body composition: A Higher body fat percentage can store MDMA metabolites longer, causing extended detection times. Muscle mass and hydration levels also affect how efficiently the drug is metabolized and excreted.
These factors collectively determine the duration MDMA and its metabolites remain detectable in the body, influencing the timeline for drug testing and the effects wearing off.
How Long Does MDMA Stay in Urine?

MDMA (3,4-methylenedioxymethamphetamine) stays in urine for about 2 to 4 days after ingestion. This duration occurs because once MDMA enters the bloodstream, it is metabolized primarily by the liver into various metabolites, which are then excreted through urine. The parent drug and its metabolites can be detected in urine during this excretion phase, which varies slightly depending on dosage, metabolism, and frequency of use.
How Long Does MDMA Stay in Blood?
MDMA stays in the blood MDMA stays in saliva for about 1 to 2 days after ingestion. It is absorbed quickly into the bloodstream and reaches peak levels about 2 hours after consumption. Due to its relatively short half-life (6-9 hours), MDMA concentrations decline rapidly as the drug is metabolized and cleared from the bloodstream.
How Long Does MDMA Stay in Saliva?
MDMA stays in saliva for 1 to 2 days (24 to 48 hours) after consumption. This is because MDMA is ingested orally and is quickly present in saliva, making it immediately detectable. The detection window for saliva tests reflects recent use, with MDMA being cleared from saliva within this timeframe under usual circumstances.
The half-life of MDMA is about 8 hours, so it is reduced significantly in the body within this period, and most of it is cleared after around 40 hours. However, the exact detection time can vary depending on factors like dosage, individual metabolism, and frequency of use.
How Long Does MDMA Stay in Hair?
MDMA can be detected in hair after 90 days or longer, depending on hair length and testing methods. This is because MDMA metabolites enter the tiny blood vessels supplying hair follicles and become incorporated into the hair shaft, where they remain until the hair grows or is cut.
What are the common withdrawal symptoms of MDMA?
The common withdrawal symptoms of MDMA include fatigue, depression, anxiety, irritability, sleep disturbances, and difficulty concentrating.
The common withdrawal symptoms of MDMA are listed below.
- Fatigue: After the stimulating effects of MDMA wear off, the brain struggles to restore normal energy levels, leaving individuals feeling exhausted. This fatigue can be so intense that it becomes difficult to get out of bed or even wake up to normal alarms.
- Depression: MDMA affects serotonin levels in the brain, and withdrawal leads to a sharp drop in serotonin, causing persistent feelings of sadness, hopelessness, and emotional numbness. This depression can be severe and often contributes to the difficulty in quitting MDMA.
- Anxiety: Without the drug’s serotonin boost, users may experience heightened anxiety or feelings of unease and restlessness. These anxious symptoms can appear shortly after stopping the drug and may linger for weeks.
- Irritability: Mood swings and a low tolerance for frustration are common during withdrawal, leading to irritability and restlessness. Small setbacks or annoyances may trigger disproportionate emotional reactions during this phase.
- Sleep disturbances: Withdrawal often disrupts sleep patterns, causing insomnia, vivid and unpleasant dreams, or hypersomnia (excessive tiredness). Sleep problems worsen the overall sense of fatigue and emotional instability.
- Difficulty concentrating: Cognitive impairments such as poor concentration, memory problems, and mental sluggishness occur as the brain attempts to regain its normal functioning. These difficulties can affect daily activities and work during the withdrawal period.
Each of these symptoms can vary in intensity depending on the individual, the duration and amount of MDMA use, and other health factors.
How to Get MDMA Out of Your System?
To get MDMA out of your system, the body primarily relies on its natural metabolic and elimination processes, hydration, rest, and recovery, avoiding additional substance use and professional detox.
The following are ways of getting MDMA out of your system.
- Natural Metabolism: MDMA is metabolized mainly by the liver. It has a half-life of about 8 hours, meaning half of the drug is reduced in the bloodstream every 8 hours, and it takes roughly 40 hours (5 half-lives) for about 95% of MDMA to be eliminated naturally.
- Hydration: Drinking water helps maintain kidney function and supports the body’s natural detox processes, but does not accelerate MDMA elimination significantly.
- Rest and Recovery: Allowing the body to rest helps the liver and kidneys function optimally in processing and clearing MDMA.
- Avoiding Additional Substance Use: Not consuming other substances ensures the liver is not further burdened, promoting more effective metabolism of MDMA.
- Professional Detox and Treatment: For those who have used MDMA heavily or frequently, professional detox programs provide medical supervision to manage withdrawal symptoms and support safe elimination.
No home remedies or quick fixes (like excessive water intake or excessive exercise) reliably speed up the clearance of MDMA. The drug’s elimination primarily depends on the body’s metabolism and function over time.
What Is MDMA?
MDMA, or 3,4-methylenedioxymethamphetamine, is a synthetic drug known commonly as ecstasy (tablet form) or molly (crystal form). It is an entactogen with stimulant and mild psychedelic properties that alters sensations, increases energy, empathy, and pleasure, and is often used recreationally at parties and raves. Originally developed in 1912, MDMA has some therapeutic use in psychotherapy but is primarily known for its euphoric effects and has a risk of harmful side effects.
How Long Do the Effects of Alcohol Last?
The effects last about 3 to 6 hours, with the peak occurring around 2 to 3 hours after use. The experience involves euphoria, increased sociability, sensory enhancement, and physical effects like jaw clenching and sweating. After the peak, users may experience an afterglow of positive feelings for several hours that gradually subside.

How Long Does it Take to Get Addicted to MDMA?
To get addicted to MDMA, it can develop through repeated use, though it is more of a psychological dependence than a physical one. People may start using it out of curiosity, peer pressure, or to cope with stress. Over time, the brain’s reward system adapts, requiring higher doses to achieve the same effects, and users may continue due to adverse comedown effects like depression and anxiety. The timeline to addiction varies individually and is influenced by usage frequency and psychological factors.
How to treat MDMA addiction?
Treatment for MDMA addiction involves comprehensive programs including medically-assisted detoxification to manage withdrawal symptoms and various types of therapy such as Cognitive Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and family therapy to address emotional regulation, coping mechanisms, and support systems.
Rehab programs play a crucial role in providing structured environments for recovery. Education and relapse prevention strategies are also key components in helping individuals maintain sobriety and rebuild their lives. Deaddiction centers often offer these integrated approaches to support long-term recovery from MDMA addiction.